David A Calderwood Selected Research

Myeloid Leukemia (Leukemia, Myelocytic)

8/2011

The E3 ubiquitin ligase specificity subunit ASB2α targets filamins for proteasomal degradation by interacting with the filamin actin-binding domain.

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David A Calderwood Research Topics

Disease

9	Neoplasms (Cancer) 01/2024 - 02/2004
4	Central Nervous System Cavernous Hemangioma 11/2020 - 02/2014
3	Melanoma (Melanoma, Malignant) 05/2023 - 01/2013
2	Leukemia 09/2011 - 12/2008
2	Acute Promyelocytic Leukemia 09/2011 - 12/2008
1	Inborn Genetic Diseases (Disease, Hereditary) 10/2018
1	Colorectal Neoplasms (Colorectal Cancer) 01/2016
1	Hemorrhagic Stroke 03/2015
1	Nervous System Diseases (Neurological Disorders) 03/2015
1	Seizures (Absence Seizure) 03/2015
1	Vascular Remodeling 01/2015
1	Hypoxia (Hypoxemia) 01/2015
1	Nephrotic Syndrome (Syndrome, Nephrotic) 03/2014
1	Albuminuria 03/2014
1	Cardiomyopathies (Cardiomyopathy) 12/2012
1	Group II Malformations of Cortical Development 08/2012
1	Fibrosarcoma 08/2012
1	Myeloid Leukemia (Leukemia, Myelocytic) 08/2011
1	Inflammation (Inflammations) 09/2006
1	Neoplasm Metastasis (Metastasis) 09/2006
1	Poikiloderma of Kindler 02/2004

Drug/Important Bio-Agent (IBA)

9	Proteins (Proteins, Gene)FDA Link 11/2020 - 02/2004
6	IntegrinsIBA 03/2015 - 02/2004
3	FilaminsIBA 08/2012 - 12/2008
3	Tretinoin (Retinoic Acid)FDA LinkGeneric 09/2011 - 12/2008
2	CytokinesIBA 01/2024 - 12/2008
1	Interferon Type IIBA 05/2023
1	Interferon alpha-beta Receptor (Receptor, Interferon alpha beta)IBA 05/2023
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2021
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2021
1	Actins (F Actin)IBA 10/2018
1	CalponinsIBA 10/2018
1	Small Interfering RNA (siRNA)IBA 01/2016
1	A-factor (Streptomyces)IBA 01/2016
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 03/2015
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2015
1	Laminin (Merosin)IBA 03/2014
1	LigandsIBA 03/2014
1	CalpainIBA 03/2014
1	Peptides (Polypeptides)IBA 01/2013
1	Matrix Metalloproteinases (MMPs)IBA 08/2012
1	Protein Isoforms (Isoforms)IBA 09/2011
1	Oncogene Proteins (Oncogene Protein)IBA 09/2011
1	Retinoic Acid Receptors (Retinoic Acid Receptor)IBA 09/2011
1	Metalloproteases (Metalloproteinases)IBA 09/2006
1	Peptide Hydrolases (Proteases)FDA Link 09/2006
1	DisintegrinsIBA 09/2006
1	Transforming Growth Factor beta1 (TGF beta 1)IBA 02/2004
1	Transforming Growth Factor beta (TGF-beta)IBA 02/2004

Therapy/Procedure

2	Therapeutics 01/2021 - 01/2016
1	Immunotherapy 01/2024